Pilonidal disease is a benign condition
Midtgaard, H.G.; Eiholm, S.
Ugeskrift for Laeger 174(46): 2855-2859
2012
ISSN/ISBN: 1603-6824 PMID: 23153466 Document Number: 656592
Malignant transformation in pilonidal disease is rare and never reported in Denmark. There are 75 cases in the literature, mostly squamous cell carcinoma. The cost-benefit of routine histological examination of specimens from pilonidal surgery is questionable, as malignancy is extremely rare. Due to increased incidence of cancer, specimens from patients with many years of pilonidal disease, known immunodeficiencies and/or human papillomavirus infection or clinical abnormal presentation, should always be investigated.