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The role of interleukin-1 and associated cytokines in gastric carcinogenesis

Matveeva, L.V.; Mosina, L.M.

Vestnik Rossiiskoi Akademii Meditsinskikh Nauk 11: 59-65

2012

ISSN/ISBN: 0869-6047
PMID: 23457983
Document Number: 656485
This review presents detailed analysis of scientific data on influence of the associated with interleukin-1 cytokines on the development of malignant tumors of stomach with the definition of spectrum of diagnostic and therapeutic possibilities. Cytokines associated with interleukin-1 directly and indirectly involved into gastric carcinogenesis. Implementation of pro- and contreoncogenic effects depends on many factors. The serological and genetic criteria changes of interleukin-1 have high diagnostic value and prognostic significance opening new differential approaches to the treatment of precancer conditions and gastric cancer.

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