Building of defects of the bladder wall by membrane, created on the basis of type i collagen (an experimental study)
Kamalov, A.A.; Mksimov, V.A.; Kirpatovskiĭ, V.I.; Kudriavtsev, I.V.; Karpov, V.K.; Tokarev, F.K.; Kamalov, D.M.; Burov, V.N.; Okhobotov, D.A.
Urologiia 6: 33-36
2012
ISSN/ISBN: 1728-2985 PMID: 23379236 Document Number: 656440
Experimental study was performed on 24 Chinchilla rabbits, which underwent resection of the bladder with building of defect by membrane "Collost", created on the basis of type I collagen. The functional state of the bladder in situ was assessed by infusion cystomanometry during repeated surgery at 7, 14 day and at 1, 3, 6 months, and at 1 and 1.5 years. It is found that developing detrusor pressure during bladder contractions was decreased by 10 times in the first week of the study; it was in line with the subcompensation after 3 months, and was restored at 6 month. At 1 and 1.5 years, increase of cumulative function of bladder while saving detrusor pressure was observed. Dilating cystoplastics using biopolymer "Collost" provides good long-term functional results.