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Pharmacological effects of Abies polyprenols and carsil on alcohol-induced hepatitis

Vaĭs, E.V.; Khyrshkaĭnen, T.V.; Tursunova, N.V.; Khushbaktova, Z.A.; Syrov, V.N.; Kuchin, A.V.

Eksperimental'naia i Klinicheskaia Farmakologiia 75(4): 26-29

2012

ISSN/ISBN: 0869-2092
PMID: 22702108
Document Number: 656199
The introduction of polyprenols isolated from fir (Abies) tree in male rats weighing 170 - 180 g with alcohol-induced hepatitis favored reduction in hepatocyte cytolysis and cholestasis and led to an improvement of the protein- and glycogen-synthesizing function of liver. A clear tendency to normalization of the maintenance of total lipids, triglycerides and phospholipids and the inhibition of lipid peroxidization processes in the damaged organ was observed. The introduction of Abies polyprenols also improved the process of bile secretion and its chemical composition.

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