Unusual work schedule: mathematical and pharmacokinetic models to adjust the occupational exposure limit of the chemical agents
Maina, G.; Cafaro, R.; Sorasio, D.; Rossi, F.
Giornale Italiano di Medicina del Lavoro Ed Ergonomia 33(3 Suppl): 28-30
2011
ISSN/ISBN: 1592-7830 PMID: 23393793 Document Number: 654341
Exposure to chemicals in unusual work shifts can require adjustment of the occupational limit values to assure adequate protection of the exposed workers. The study introduces a comparative analysis of the mathematical and pharmacokinetic models to calculate the adjustment factors and provides a computer-assisted toolkit to obtain the reduction factors for exposures to single chemical agent and mixtures in unusual work schedule.