Gastric cancer: genetic and molecular abnormalities
Torres-Jasso, J.H.; Sánchez-López, J.Y.
Gaceta Medica de Mexico 147(1): 72-73
2011
ISSN/ISBN: 0016-3813 PMID: 21412400 Document Number: 654324
In this work, the genetic and molecular alterations involved in gastric carcinogenesis are shown; the affected genes are those that encoded for matrix metalloproteinases, cell growth factors and receptors, oncogenes, tumor suppressors, DNA repair and cell adhesion molecule genes, cell cycle regulators and others related to metastasis, as well as lost of heterozygosity in chromosomal regions.