Statins can maybe reduce the risk of venous thromboembolism
Toft-Petersen, A.Pernille.; Thomsen, R.Wernich.; Schmidt, E.Berg.; Larsen, T.Bjerregaard.
Ugeskrift for Laeger 173(22): 1558-1563
2011
ISSN/ISBN: 0041-5782 PMID: 21627898 Document Number: 653523
Recent reports suggest beneficial effects of statin treatment on risk of venous thromboembolism (VTE). This review studies the existing literature on statins and VTE: one meta-analysis, one randomized controlled trial, four cohort studies and eight case-control studies. The hypothesis of a risk reducing effect of statins on recurrent VTE is supported, but the included studies are heterogeneous; and there is a risk of uncontrolled confounding. Randomized clinical trials aimed at clarifying whether statins can prevent recurrent VTE or not are warranted.