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Evaluation of the potential risk of porcine endogenous retrovirus (PERV) infection in nude mice

Bae, E.H.; Jung, Y.-T.

Journal of Microbiology and Biotechnology 21(4): 387-390

2011

ISSN/ISBN: 1738-8872
PMID: 21532322
Document Number: 652888
Nude mice (BALB/c) were grafted with human 293 cells and PERV (porcine endogenous retrovirus)-IRES-EGFP (a packageable retroviral vector plasmid containing an internal ribosome entry site-enhanced green fluorescent protein)-producing pig PK15 cells in order to determine whether the pig cells could transmit PERV-IRES-EGFP to mice and human 293 cells in vivo. None of the transplanted human 293 cell lines were infected by PERV, but PCR analysis identified PERV-B provirus integration into both the heart and salivary gland of the inoculated nude mice. Our data indicate that hearts and salivary glands can be used to identify PERV-B receptors.

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Karlas, A.; Irgang, M.; Votteler, J.ör.; Specke, V.; Ozel, M.; Kurth, R.; Denner, J. 2010: Characterisation of a human cell-adapted porcine endogenous retrovirus PERV-A/C Annals of Transplantation 15(2): 45-54
Klein, J.R.; Bevan, M.J. 1983: Secretion of immune interferon and generation of cytotoxic T cell activity in nude mice are dependent on interleukin 2: age-associated endogenous production of interleukin 2 in nude mice Journal of Immunology 130(4): 1780-1783
Davalli, A.M.; Ogawa, Y.; Scaglia, L.; Wu, Y.J.; Hollister, J.; Bonner-Weir, S.; Weir, G.C. 1994: Porcine islet grafts in diabetic nude mice: dynamic insulin secretion and regulated B-cell mass lower glucose levels to the normal porcine range Transplantation Proceedings 26(3): 1098-1099
Korbutt, G.S.; Ao, Z.; Warnock, G.L.; Flashner, M.; Rajotte, R.V. 1995: Successful reversal of diabetes in nude mice by transplantation of microencapsulated porcine neonatal islet cell aggregates Transplantation Proceedings 27(6): 3212
Rayat, G.R.; Rajotte, R.V.; Ao, Z.; Korbutt, G.S. 2000: Microencapsulation of neonatal porcine islets: protection from human antibody/complement-mediated cytolysis in vitro and long-term reversal of diabetes in nude mice Transplantation 69(6): 1084-1090
Hanna, N.; Fidler, I.J. 1981: Expression of metastatic potential of allogenic and xenogeneic neoplasms in young nude mice Cancer Research 41(2): 438-444
Jiménez Romano, R.; Gimeno Ortíz, A. 1991: Retrovirus HIV-1 and HIV-2 infection in populations at risk. Estremadura Revista de Sanidad E Higiene Publica 65(3): 239-246
Gao, J.-H.; Wang, N.; Yang, Z.-M.; Shi, X.-M.; Qian, H.-Z.; Zhang, Y.-L.; Jia, W.-Q.; Xu, C.-L.; Zheng, X.-W. 2007: Comprehensive evaluation on the potential risk for HIV infection in 12 villages with a history of former paid blood donation Zhonghua Liu Xing Bing Xue Za Zhi 28(7): 656-658
Jessup, J.M.; Giavazzi, R.; Campbell, D.; Cleary, K.R.; Morikawa, K.; Hostetter, R.; Atkinson, E.N.; Fidler, I.J. 1989: Metastatic potential of human colorectal carcinomas implanted into nude mice: prediction of clinical outcome in patients operated upon for cure Cancer Research 49(24 Part 1): 6906-6910
Jessup, J.M.; Giavazzi, R.; Campbell, D.; Cleary, K.; Morikawa, K.; Fidler, I.J. 1988: Growth potential of human colorectal carcinomas in nude mice: association with the preoperative serum concentration of carcinoembryonic antigen in patients Cancer Research 48(6): 1689-1692
Fukatsu, H.; Yamada, H.; Nonomura, H.; Miyagawa, Y.; Hatano, Y.; Waki, M.; Hiraiwa, S.; Muramatsu, T.; Yamada, Y.; Nishikawa, E. 1987: Study on heterotransplantation of human malignant urogenital tumors in nude mice: establishment of the tumor line in nude mice from human primary ureteral tumor and its characteristics Hinyokika Kiyo. Acta Urologica Japonica 33(12): 1943-1950
Schlegerová, D.; Kubín, M.; Holub, M. 1978: Lymphatic tissues of nude mice during early stages of Mycobacterium kansasii infection Folia Biologica 24(6): 428-429
Stevens, D.P.; Frank, D.M.; Mahmoud, A.A. 1978: Thymus dependency of host resistance to Giardia muris infection: studies in nude mice Journal of Immunology 120(2): 680-682
Christensen, T.; Pedersen, L.; Sørensen, P.D.; Møller-Larsen, A.é 2002: A transmissible human endogenous retrovirus Aids Research and Human Retroviruses 18(12): 861-866
Yamada, T.; Tanase, M.; Watanabe, A.; Sawada, H.; Yamada, Y.; Shino, Y.; Yamashita, J.; Matsuda, M.; Nakano, H. 1997: Evaluation of combination chemotherapy with 5-FU and CDDP for human gastric carcinoma transplanted into nude mice Gan to Kagaku Ryoho. Cancer and ChemoTherapy 24(1): 43-47
Sordillo, P.P.; Helson, L.; Lesser, M. 1980: Evaluation of 4'-(9-acridinylamino) methanesulfon-m-anisidide (m-AMSA, NSC 249992) on human tumors in nude mice Cancer Clinical Trials 3(4): 385-389
Shephard, S.E.; Schlatter, C.; Lutz, W.K. 1987: Model risk analysis of nitrosatable compounds in the diet as precursors of potential endogenous carcinogens Iarc Scientific Publications 84: 328-332
Gotoh, A.; Mizuno, Y.; Matsuwari, S.; Kitazawa, S.; Maeda, S.; Arakawa, S.; Kamidono, S. 1994: Evaluation of the anticancer effect of cisplatin and etoposide against nude mice transplanted urological malignant tumors Gan to Kagaku Ryoho. Cancer and ChemoTherapy 21(6): 899-902
Pechik, I.V.; Andreeva, N.S. 1999: A model of the three-dimensional structure of human endogenous retrovirus protease Molekuliarnaia Biologiia 33(6): 1035-1042
Zhang, J.-y.; Feng, J.; Li, H.-m.; Li, X.-d.; Jia, H.-l. 2011: Comparison of the biodistribution of four contrast agents in nude mice bearing NCI-H358 human lung cancer and evaluation of their value in diagnostic imaging Zhonghua Zhong Liu Za Zhi 33(7): 504-507