Exercise induced fatigue: unfit or unwell?

Moore, D.M.; Nadarajan, P.; Hawksworth, R.; Lane, S.J.; Graham, I.M.; Moore, D.M; Nadarajan, P; Hawksworth, R; Lane, S.J; Graham, I.M

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Exercise induced fatigue: unfit or unwell?

Moore, D.M.; Nadarajan, P.; Hawksworth, R.; Lane, S.J.; Graham, I.M.

Irish Medical Journal 104(5): 151

2011

ISSN/ISBN: 0332-3102

PMID: 21736093

Document Number: 652757

This case report outlines the diagnoses of a rare myophosphorylase deficiency (McArdle Syndrome) in a unique way. A set of characteristic values from a Cardiopulmonary Exercise Test (CPET) combined with a typical patient history pointed to a failure of the glycolytic pathway in the skeletal muscle. McArdle Syndrome was confirmed with a skeletal muscle biopsy. There is no evidence of such a diagnostic method in the literature.