Application of hyperbaric oxygen therapy for post-cardiac arrest syndrome
Miyamoto, K.; Dohi, K.
Nihon Rinsho. Japanese Journal of Clinical Medicine 69(4): 648-652
2011
ISSN/ISBN: 0047-1852 PMID: 21591418 Document Number: 651585
Therapeutic mechanisms of hyperbaric oxygen therapy (HBOT) are based on elevation of both the partial pressure of oxygen and hydrostatic pressure. It has been reported that HBOT supply much amount of oxygen and might prevent from brain tissue after global ischemia in patients with post-cardiac arrest syndrome(PCAS). On the other hand, high levels of oxygen produce reactive oxygen species(ROS). ROS occurs secondary brain damage after ischemia. The clinical evidence of HBOT has not been established. In this paper, we review some reports about the advantages and disadvantages of HBOT after global ischemia with PCAS.