Advantage and disadvantages of single-pill (fixed) antihypertensive drug combinations
Umemura, S.
Nihon Rinsho. Japanese Journal of Clinical Medicine 69(11): 2042-2048
2011
ISSN/ISBN: 0047-1852 PMID: 22111328 Document Number: 651555
It is evident that BP reduction per se is the primary determinant of CV risk reduction. And more than half patients will require combination therapy to achieve contemporary BP targets. Single-pill combination can be used for this purpose. Advantages of using an single-pill combination may include convenience, less expensive, fewer pills, less time to achieve BP control and improving adherence. Disadvantages will also be discussed.