The use of silymarin in patients with toxic and viral liver diseases
Matveev, A.V.; Koniaeva, E.I.
Eksperimental'naia i Klinicheskaia Gastroenterologiia 5: 84-90
2011
ISSN/ISBN: 1682-8658 PMID: 21916240 Document Number: 651143
Effective use of Silybum marianum medicines is still urgent in hepatology practice. Data about effectiveness and safety of silymarin in patients with acute and chronic toxic injuries including drug-induced ones and patients with acute and chronic viral hepatitis is reviewed in the article. An attempt of trials limitations and disadvantages systematization is made and methods of their solvation are discussed. A possibility of silymarin use as antiviral agent in patients with chronic hepatitis C is also reviewed and perspectives of this drug clinical use in future is discussed.