Mechanisms of hypermetabolic states
Élbakidze, G.M.; Élbakidze, A.G.
Vestnik Rossiiskoi Akademii Meditsinskikh Nauk 7: 50-54
2011
ISSN/ISBN: 0869-6047 PMID: 21899093 Document Number: 650870
Current concepts of mechanisms of hypermetabolic states in the body and its selected organs are discussed. Special attention is given to hepatic processes and changes of energy metabolism in hypermetabolic hepatocytes. It is shown that hypermetabolic cells have properties characteristic of the metabolism stimulation phase in cells showing a non-specific reaction to an injury. Differences between cellular hypermetabolism and stimulated metabolism in an injured cell are considered. It is hypothesized that hypermetabolism at the cellular level may be regarded as a stably prolonged phase of stimulated metabolism related to the cell non-specific reaction to an injury.