Assessment of moisturizing creams available in México
Hernández-Barrera, N.R.; Moncada, B.ín.; Navarrete-Solís, J.; Fuentes-Ahumada, C.; Torres-Álvarez, B.; Castanedo-Cázares, J.P.; Cano-Ríos, P.
Gaceta Medica de Mexico 147(3): 270-274
2011
ISSN/ISBN: 0016-3813 PMID: 21743598 Document Number: 650780
There is a broad diversity of moisturizers for the treatment of dry skin; however, we do not know their real effectiveness. The objective here was to evaluate different products through their capacity to increase the epidermal hydration level (EHL) and to reduce the transepidermal water loss (TEWL). We evaluated twenty moisturizers in sixteen individuals. The analysis was made on volar forearm and basal measurements were made for EHL and TWEL with the later application of 8 gm of each moisturizer on a 2 cm2 area. For the EHL we found significant differences among the products (p < 0.0001), but only 35% (n = 7) of the moisturizers registered ascending levels of hydration in the course of measurements. The variance analysis for TEWL also was significant (p < 0.0001). In the short term only a few products induced a significant change in EHL. This study demonstrates the necessity to obtain objective information in order to avoid false publicity claims that may erroneously influence our prescription habits.
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