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Free radical oxidation of lipids in the rat hypothalamus under stress after cortisol pretreatment

Flerov, M.A.; V'iushina, A.V.

Rossiiskii Fiziologicheskii Zhurnal Imeni I.M. Sechenova 97(9): 898-902

2011

ISSN/ISBN: 0869-8139
PMID: 22165201
Document Number: 650666
Free radical oxidation of lipids in the rat hypothalamus after cortisol pretreatment weas investigated. Three-fold cortisol injection (25 mg/kg, once per day) resulted in significant decrease of average level of Schiffbases, the final products of lipid oxidation. Stress causes increase of average level of Schiff bases in the control animals (without cortisol pretreatment). Cortisol pretreatment potentiated stress-induced changes in the processes of free radical oxidation of lipids in the rats hypothalamus.

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