Vernakalant--a new drug for pharmacological conversion of atrial fibrillation
Hinneburg, I.
Medizinische Monatsschrift für Pharmazeuten 34(5): 154-158
2011
ISSN/ISBN: 0342-9601 PMID: 21644373 Document Number: 649697
Vernakalant is a new antiarrhythmic drug which is used for rapid conversion of atrial fibrillation. The drug is a relatively atrium-selective K' and Na+ channel blocker, prolonging the atrial refractory period. Clinical trials showed conversion rates of about 50% which is comparable to other antiarrhythmic drugs. Further trials will show if vernakalant is less pro-arrythmogenic than its competitors.
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