Extended thymectomy and intraoperative-intrapleural perfusion hyperthermo-chemotherapy for stage IVa invasive thymoma with myasthenia gravis
Matsuba, T.; Nakamura, Y.; Fukumori, K.; Nagata, T.; Imoto, Y.; Tabata, K.
Kyobu Geka. Japanese Journal of Thoracic Surgery 64(5): 398-401
2011
ISSN/ISBN: 0021-5252 PMID: 21591443 Document Number: 648347
A 37-year-old woman diagnosed with ocular myasthenia gravis was referred to our department. Chest computed tomography (CT) showed anterior mediastinal tumor and right pleural dissemination. Extended thymectomy and right intraoperative-intrapleural perfusion hyperthermo-chemothrapy (IPHC) were performed. Pathological diagnosis was invasive thymoma type B2 and stage IVa based on Masaoka's classification. The post operative course was uneventful. The patient underwent 4 cycles of adjuvant chemotherapy with doxorubicin, cisplatin, vincristine, and cyclophosphamide (ADOC), and is free from recurrence at 12 months postoperatively.