Asymptomatic celiac disease in patient with chronic acalculous cholecystitis
Parfenov, A.I.; Dolgasheva, G.M.; Krums, L.M.; Bystrovskaia, E.V.; Sabel'nikova, E.A.; Gudkova, R.B.; Vorob'eva, N.N.; Lishchinskaia, A.A.
Eksperimental'naia i Klinicheskaia Gastroenterologiia 3: 122-124
2011
ISSN/ISBN: 1682-8658 PMID: 21695960 Document Number: 648219
We described a patient 40 years old, admitted to the clinic with periodic attacks of pain in the right upper quadrant. With ultrasound it was confirmed chronic acalculous cholecystitis, and at endoscopy and multiple biopsies revealed atrophy of the mucosa of the duodenum (DM), corresponding to celiac disease (stage III in the Marsh classification). Titer of antibodies to gliadin (AGA) and tissue transglutaminase (AtTG) were higher: 60 and 110 units/ml, respectively, at a rate of 10 units/ml. The patient was assigned a lifetime adherence to a gluten-free diet, serologic test and a control endoscopy with biopsy at 6 months. The important role of the doctor-endoscopist in the diagnosis of latent forms of celiac disease. The significance of DM atrophy in the pathogenesis of patients with chronic cholecystitis.