Retreatment with peginterferon plus ribavirin in chronic hepatitis C patients: our own experiences
Roznovský, L.; Orságová, I.; Petrousová, L.; Mrázek, J.; Kloudová, A.; Kabieszová, L.; Kůrková, J.; Pospísek, M.
Klinicka Mikrobiologie a Infekcni Lekarstvi 16(2): 73-75
2010
ISSN/ISBN: 1211-264X PMID: 20503159 Document Number: 647816
Retreatment with peginterferon plus ribavirin was initiated in 26 patients with hepatitis C virus genotype 1b infection (17 relapsers after the first course of therapy, 9 non-responders). So far, retreatment has been completed in 19 patients, one patient achieved a sustained virologic response, and 3 patients were relapsers. Therapy was discontinued in 14 patients (9 non-responders) because of a lack of a treatment response, and in 1 patient due to adverse effects. Retreatment is a new chance for patients with chronic hepatitis C infection. However successful outcome is rare especially in non-responders.