Postvaricella purpura fulminans with no evidence of disseminated intravascular coagulation (DIC) or protein S deficiency
Sharma, V.K.; Dubey, T.N.; Dave, L.; Agarwal, A.
Journal of the Indian Medical Association 108(8): 529-530
2010
ISSN/ISBN: 0019-5847 PMID: 21404754 Document Number: 646682
The mechanism of postvaricella purpura fulminans is thought to be due to development of antiprotein S antibodies. These antibodies lead to an acquired transient severe protein S deficiency which results in disseminated intravascular coagulation and microvascular thrombosis. Here a patient presented with postvaricella purpura fulminans, where no clinical or laboratory evidence of disseminated intravascular coagulation could be found and there was no deficiency of protein S.