Growth factors are markers of placental insufficiency in third-trimester miscarriage
Kuznetsova, R.A.; Rachkova, O.V.; Kulida, L.V.; Kruglova, L.V.; Peretiatko, L.P.
Arkhiv Patologii 72(6): 40-43
2010
ISSN/ISBN: 0004-1955 PMID: 21400782 Document Number: 645096
The paper characterizes placental growth factors in the third trimester of pregnancy. The placental expression of vascular endothelial growth factor (VEGF) and transforming growth factor-beta2 (TGFbeta2) was studied in miscarriage after 34-37 weeks pregnancy and during term labor. Chronic placental insufficiency was diagnosed in miscarriage. The expression of VEGF and TGFbeta2 with trophoblast and decidual cells was decreased in miscarriage as compared with that during uncomplicated pregnancy. The growth factors under study are markers of chronic placental insufficiency in third-trimester miscarriage.