Detoxicating properties of remaxol with respect to multiple organ failure during severe ethanol poisoning
Sivak, K.V.; Savateeva-Liubimova, T.N.; Petrov, A.I.; Kovalenko, A.L.
Eksperimental'naia i Klinicheskaia Farmakologiia 73(12): 39-43
2010
ISSN/ISBN: 0869-2092 PMID: 21395017 Document Number: 645038
Experiments on male rats showed that severe alcohol poisoning results in a multiple organ failure followed by functional impairment of heart, liver and kidney. Intensive infusion therapy with remaxol was found to significantly restore the functional activity and morphological structure of the target organs of ethanol intoxication. The results suggest that remaxol possesses antihypoxic, detoxicating, and hepatic and renal protective properties with respect to severe ethanol intoxication.