Study of incidence and correlation factors of depression, anxiety and insomnia in patients with myasthenia gravis
Qiu, L.; Feng, H.-y.; Huang, X.; Mo, R.; Ou, C.-y.; Luo, C.-m.; Li, Y.; Liu, W.-b.
Zhonghua Yi Xue Za Zhi 90(45): 3176-3179
2010
ISSN/ISBN: 0376-2491 PMID: 21223762 Document Number: 644958
To investigate the incidence rate and correlation factors of depression, anxiety and insomnia in patients with myasthenia gravis (MG). A total of 161 MG patients were assessed and graded with HAMD, HAMA, PSQI, QMG, ADL and a self-made scale chart. And the correlation factors were analyzed by Logistic stepwise regression. The prevalence of depression, anxiety and insomnia was 58.3%, 45.3% and 39.1% respectively. The correlation factors with significant influences on MG were as follows: depression with age, physical weakness, score of QMG, life scale grading; anxiety with experience-sharing; insomnia age, dyspnea, thymoma, physical status at 1 month post-operation, prednisone dose and score of QMG. Nearly one half of the MG patients suffer from affective disorders to different degrees. And an analysis of its correlation factors provides references to prevent and treat the affective disorders concurrently with MG.