Analysis of the changes in the cellular populations of the pancreatic pseudocyst in an experiment
Doroshkevich, S.V.; Pivchenko, P.G.; Doroshkevich, E.I.
Morfologiia 137(2): 53-56
2010
ISSN/ISBN: 1026-3543 PMID: 20572396 Document Number: 643518
The purpose of the research was to study, using the quantitative methods, the cellular populations of neutrophilic granulocytes, macrophages, fibroblasts and lymphocytes in the connective tissue of the wall of the pancreatic pseudocyst. Local cold application to the pancreas of albino rat with the help of KCH 3A/B cryosurgical complex was used for the modeling of the pseudocyst. General decrease in the cell content in wall of the pseudocyst was detected together with the changes of predominant cell populations during the study. At days 14-21 of the experiment, the neutrophilic granulocytes were found to dominate, by day 30 the dominating cells were the macrophages, which were substituted by fibroblasts at day 45. The progressive increase of the number of lymphocytes was found throughout the the experiment.