Rapid detection of caffeine in blood by freeze-out extraction
Bekhterev, V.N.; Gavrilova, S.N.; Kozina, E.P.; Maslakov, I.V.
Sudebno-Meditsinskaia Ekspertiza 53(5): 22-24
2010
ISSN/ISBN: 0039-4521 PMID: 21265179 Document Number: 642544
A new method for the detection of caffeine in blood has been proposed based on the combination of extraction and freezing-out to eliminate the influence of sample matrix. Metrological characteristics of the method are presented. Selectivity of detection is achieved by optimal conditions of analysis by high performance liquid chromatography. The method is technically simple and cost-efficient, it ensures rapid performance of the studies.
Document emailed within 1 workday
Related Documents
Challans, J.A.; Stevenson, K.; Reid, H.W.; Sharp, J.M. 1994: A rapid method for the extraction and detection of Mycobacterium avium subspecies paratuberculosis from clinical specimens Veterinary Record 134(4): 95-96Bucher, H.U.; Gautschi, K. 1985: Detection of caffeine, theophylline and theobromine in the umbilical cord blood and breast milk Helvetica Paediatrica Acta 40(2-3): 163-167
Hai, L.; Sun, H.; Li, Z. 1998: Simultaneous extraction of tea-polyphenols and caffeine from green tea Wei Sheng Yan Jiu 27(3): 195-196
Firth, N.L.; Ross, D.A.; Thonney, M.L. 1985: Comparison of ether and chloroform for Soxhlet extraction of freeze-dried animal tissues Journal - Association of Official Analytical Chemists 68(6): 1228-1231
Sacchi, E.; Duca, F.; Tagliabue, L. 1996: Rapid detection of factor V: Q506 mutation using whole blood protein C resistance Blood Coagulation and Fibrinolysis: An International Journal in Haemostasis and Thrombosis 7(8): 799-800
Wolf, K.V.; Stockem, W.; Wohlfarth-Bottermann, K.E. 1980: Influence of different freeze-fracture pretreatments on the fine structure of Physarum polycephalum. a freeze-fracture and freeze-substitution study European Journal of Cell Biology 22(2): 667-677
Paanakker, J.E.; Thio, J.M.; Van den Wildenberg, H.M.; Kaspersen, F.M. 1987: Assay of vecuronium in plasma using solid-phase extraction, high-performance liquid chromatography and post-column ion-pair extraction with fluorimetric detection Journal of Chromatography 421(2): 327-335
Givental', N.I.; Gritsenko, A.N.; Podosinnikova, L.S.; Kharitonova, T.I.; Arutiunov, I.I. 1973: Use of phase-contrast microscopy for the rapid detection of cholera antibodies in human blood sera Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 50(7): 50-54
Sellon, D.C.; Walker, K.; Suyemoto, M.; Altier, C. 1997: Nucleic acid amplification for rapid detection of Rhodococcus equi in equine blood and tracheal wash fluids American Journal of Veterinary Research 58(11): 1232-1237
Zheng, X.; Hu, X. 2006: Rapid analysis of two intermediates in caffeine synthesis by RP-HPLC Se Pu 24(2): 205
Gale, G.R.; Smith, A.B. 1988: Interaction of caffeine with acetaminophen in mice: schedule dependency of the antagonism by caffeine of acetaminophen hepatotoxicity and the effects of caffeine metabolites, allopurinol, and diethyl ether Research Communications in Chemical Pathology and Pharmacology 59(3): 305-320
Cuellar-Rodríguez, J.M.; Ponce-De-León, A.; Quiroz-Mejía, R.; Galindo-Fraga, A.; Rolón-Montes-de-Oca, A.L.; Hernández-Durán, M.; Ruiz-Palacios, G.M.; Sifuentes-Osornio, J.é 2009: Rapid detection of ESBL-producing gram-negative bacteria isolated from blood: a reasonable and reliable tool for middle and low resource countries Revista de Investigacion Clinica; Organo del Hospital de Enfermedades de la Nutricion 61(4): 306-312
Klincheva, S.A.; Bakaev, V.V.; Barinskiĭ, I.F.; Gnedoĭ, S.N.; Nikolaeva, N.P. 1996: The use of nested polymerase chain reaction method for rapid detection of cytomegalovirus in peripheral blood leukocytes of patients after bone marrow transplantation Voprosy Virusologii 41(4): 147-149
Leowattana, W.; Pokum, S.; Mahanonda, N.; Poungvarin, N. 2001: Rapid detection of Chlamydia pneumoniae DNA in peripheral blood mononuclear cells of coronary artery disease patients by real-time fluorescence PCR Journal of the Medical Association of Thailand 84(Suppl 3): S658-S668
Armstrong, M. 2012: Atrial Fibrillation with Rapid Ventricular Response following use of Dietary Supplement Containing 1,3 Dimethylamylamine and Caffeine Journal of Special Operations Medicine: a Peer Reviewed Journal for Sof Medical Professionals 12(4): 1-4
Tang, J.; Li, J.; Sun, J.; Yin, J.; He, Z. 2005: Rapid and sensitive determination of indapamide in human blood by liquid chromatography with electrospray ionization mass spectrometric detection: application to a bioequivalence study Die Pharmazie 60(11): 819-822
Pumplin, D.W.; Strong, J. 1988: Membrane domains of AChR clusters of cultured rat myotubes revealed by rapid-freeze, deep-etch, rotary-replication Puerto Rico Health Sciences Journal 7(2): 96-99
el-Yazigi, A.; Chaleby, K.; Martin, C.R. 1989: A simplified and rapid test for acetylator phenotyping by use of the peak height ratio of two urinary caffeine metabolites Clinical Chemistry 35(5): 848-851
Mayer, S.E.; Stull, J.T.; Wastila, W.B. 1974: Rapid tissue fixation and extraction techniques Methods in Enzymology 38: 1-9
Hawker, R.J. 1975: Vessel for the rapid extraction of plasma proteins Laboratory Practice 24(1): 25