The safety of hormonal contraceptives for women living with HIV and their sexual partners
Phillips, S.J.; Polis, C.B.; Curtis, K.M.
Contraception 93(1): 11-16
2016
ISSN/ISBN: 1879-0518 PMID: 26515194 DOI: 10.1016/j.contraception.2015.10.002Document Number: 640961
Hormonal contraceptives are important for the health and well-being of some women living with HIV, so evaluation of evidence regarding their safety vis-à-vis HIV-related risks is important. We updated two prior systematic reviews on the impact of hormonal contraception (HC) on HIV disease progression and female-to-male HIV transmission. One new study finds no increased risk for HIV disease progression or death associated with oral contraceptive use [adjusted (adj) hazard ratio (HR) 0.83, confidence interval [CI] 0.48-1.44] or injectables (adj HR 0.72, CI 0.53-0.98). Three new studies did not find significantly increased risks for measures of female-to-male HIV transmission with HC use. Hormonal contraceptive methods do not appear to accelerate HIV disease progression. More research is needed to clarify whether HC impacts HIV transmissibility.
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