Antiprotease activity of selected Slovak medicinal plants

Jedinak, A.; Valachova, M.; Maliar, T.; Sturdik, E.

Die Pharmazie 65(2): 137-140

2010


ISSN/ISBN: 0031-7144
PMID: 20225660
Document Number: 640761
Fifty-six methanol extracts obtained from the barks, flowers, leaves and stems of 30 Slovak trees, bushes and herbs used in the traditional medicine of the Small Carpathians, Slovakia, have been screened for antiprotease (trypsin, thrombin and urokinase) activity using chromogenic bioassay. In this study, 14 extracts showed the strong inhibition activity to protease trypsin with IC50 values below 10 micro g/mL.

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