Evaluation of pain reduction upon injecting goserelin acetate using an ice pack
Ikeda, K.; Ogawa, Y.; Nagahara, H.; Xiang, Z.; Sakurai, K.; Fukuoka, T.; Tokunaga, S.; Nishiguchi, Y.
Gan to Kagaku Ryoho. Cancer and ChemoTherapy 37(2): 291-293
2010
ISSN/ISBN: 0385-0684 PMID: 20154487 Document Number: 639983
LH-RH agonist is the key drug in hormonal therapy for premenopausal patients with breast cancer. It is important to reduce the pain related to injecting the LH-RH agonist, because patients must continue the medication for several years. We developed a way to reduce the pain by cooling the needle injecting site with a frozen ice pack. 18 premenopausal postoperated women filled out a questionnaire on the severity of pain upon injecting Goserelin acetate compared with the pain without this cooling method and pretreatment. We estimated the pain by a Numerical Rating Scale(NRS). The NRS scores of this cooling method revealed the pain to be significantly less than by control method(p<0. 005). This cooling method could be useful for the reduction of pain upon injecting the LH-RH agonist.