Intraoperative radiotherapy in multimodality treatment of locally advanced rectal carcinoma
Soumarová, R.; Skrovina, M.; Machala, S.; Adamcík, L.; Bartos, J.
Rozhledy V Chirurgii Mesicnik Ceskoslovenske Chirurgicke Spolecnosti 89(11): 685-688
2010
ISSN/ISBN: 0035-9351 PMID: 21409803 Document Number: 639348
Multimodality treatment of locally advanced rectal cancer combines radical surgery, radiotherapy and chemotherapy. This method leads to improvement of local control and overall survival. However, some of the patients incur local failure of disease, which are localized predominantly in presacral region. The integration of intraoperative radiotherapy as part of a multimodal treatment approach helps to a further dose escalation without increasing toxicity, and reduces the likelihood of otherwise difficult curable local failure.