An association of the protein spectrum and various immunoglobulin classes in synovial fluid in gonarthrosis
Luneva, S.N.; Matveeva, E.L.; Chepeleva, M.V.; Gasanova, A.G.; Spirkina, E.S.
Klinicheskaia Laboratornaia Diagnostika 2010(2): 21-23
2010
ISSN/ISBN: 0869-2084 PMID: 20401993 Document Number: 639247
Synovial fluid from patients with gonarthrosis was examined using biochemical and immunological studies; the levels of total protein, protein fractions, and immunoglobulins A, M, and G were measured. In a joint osteoarthrotic process, the patients' synovial fluid showed a significant increase in the levels of immunoglobulins of all classes and total protein, a change in the distribution of protein fractions, and a close correlation between IgM and a protein beta-globulin fraction.