The prooxidant system. Approaches to the choice of research algorithm
Pluzhnikov, N.N.; Bakulina, L.S.; Kozlov, O.S.; Iartsev, A.I.
Vestnik Otorinolaringologii 5: 72-75
2010
ISSN/ISBN: 0042-4668 PMID: 21207902 Document Number: 638064
The regulatory function of the processes involving free radicals known to maintain cellular vital activity and their role as an intermediate stage of many vitally important enzymatic reactions attract the attention of researchers interested in the mechanisms of production and inactivation of free radicals. Investigations into prooxidant and antioxidant systems along with evaluation of the intensity of free-radical oxidation make it possible to resolve many problems including elucidation of dynamic activity of pathological process, prognosis of various pathological conditions, and the choice of possible methods for the correction of prooxidant/antioxidant balance in patients with ENT diseases. The development of algorithms and methods for the assessment of parameters of activity of the prooxidant system allows for their stage by stage measurement and evaluation.