Pathomorphology of the lung in severe influenza A/H1N1
Zaĭrat'iants, O.V.; Cherniaev, A.L.; Chuchalin, A.G.; Polianko, N.I.; Kelli, E.I.; Rogov, K.A.; Mikhaleva, L.M.; Trusov, A.E.; Samsonova, M.V.; Pominal'naia, V.M.
Anesteziologiia i Reanimatologiia 3: 25-29
2010
ISSN/ISBN: 0201-7563 PMID: 20734843 Document Number: 638010
Thirty-five autopsy cases of influenza A/HIN1 in Moscow were analyzed. Primary pathological changes were found in the trachea and lung. The lung showed a pattern of the exudative and proliferative stages of diffuse alveolar damage. In addition, there were signs of infectious-toxic shock associated with viremia, as suggested by pronounced changes in the brain, kidneys, liver, spleen, adrenals, and lymph nodes. Bacterial bronchopneumonia was detected in only 20% of cases.