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The influence of hyperglycemia on functions of endothelial progenitor cells

Krawczyk, A.; Izdebska, M.; Grzanka, A.

Polski Merkuriusz Lekarski Organ Polskiego Towarzystwa Lekarskiego 26(153): 245-247

2009

ISSN/ISBN: 1426-9686
PMID: 19388542
Document Number: 637135
The isolation of endothelial progenitor cells changed our understanding of adult blood vessel formation. Recent studies have proven that EPCs functionally contribute to neovasculogenesis and reendothelization of damage blood vessels. It has been shown that patients with diabetes mellitus have decreased numbers of EPCs with impaired activities important to growth of blood vessels. It has been demonstrated that hypoglycemia cause abnormalities in EPCs proliferation, differentiation, adhesion and migration.

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