Sphenoid wing meningioma and glioblastoma multiforme in collision - case report and review of the literature
Mitsos, A.P.; Konstantinou, E.A.; Fotis, T.G.; Lafazanos, S.A.; Kontogeorgos, G.; Georgakoulias, N.V.
Neurologia i Neurochirurgia Polska 43(5): 479-483
2009
ISSN/ISBN: 0028-3843 PMID: 20054751 Document Number: 637001
The coexistence of two histologically different primary tumours in the same brain region is relatively rare. The situation where these tumours in collision appear in an area of a previously excised meningioma is even more rare and only two cases have been reported so far. We present the third case of a 73-year-old woman who underwent an uneventful excision of a right sphenoid wing meningioma. She was re-admitted 3 years later due to reappearance of a tumour in the area adjacent to the previously excised meningioma. Histological diagnosis revealed a collision tumour of a glioblastoma multiforme and a fibrillary meningioma. The coincidence of these two different neoplasms in the same location at the same time 3 years after surgical removal of a meningioma leads us to speculate on the pathogenesis, and to review the literature regarding this particular issue.