Mechanism of manganese transport regulation based on the long RNA helix in Brucella
Seliverstov, A.V.; Liubetskiĭ, V.A.
Biofizika 54(2): 222-225
2009
ISSN/ISBN: 0006-3029 PMID: 19402531 Document Number: 636908
It has been found that divalent cation transporters of the Nramp family in cell phagosomes and bacteria that parasitize on the cell compete for metals, which is crucial for bacterial survival. Long helices were determined by means of our algorithm for each mRNA in the 5'-untranslated region in Brucella. Conserved long RNA helices were found in mRNA that encode manganese transporters as well as Ni-dependent Glyoxalase I. We suggest that long helices in these regions are involved in the regulation of RNA stability.