E (y) 2, the novel component of SAGA/TFTC complex in eucaryotes participates in export of mRNP from nucleus and couples transcription with nuclear pore
Kurshakova, M.M.; Nabirochkina, E.N.; Georgieva, S.G.
Molekuliarnaia Biologiia 43(2): 253-263
2009
ISSN/ISBN: 0026-8984 PMID: 19425494 Document Number: 636378
For many years transcription was studied independently from the following stages of gene expression. However the tight connection between different stages of gene expression became evident during the last years. This review discusses the new molecular mechanisms coordinating transcription and mRNA export from the nucleus and coupling of transcription and position of the gene in the nucleus. The new protein E(y)2 which plays an important role in these processes is described.