Malignant vulvar soft tissue myoepithelioma
Mukhina, M.S.; Maksimova, N.A.; Safina, N.S.; Chizh, I.A.
Arkhiv Patologii 71(2): 18-20
2009
ISSN/ISBN: 0004-1955 PMID: 19507572 Document Number: 635593
The authors describe a case of malignant vulvar soft tissue myoepithelioma in a 41-year-old woman. Microscopically, epithelioid and spindle cells were located in the myxoid stroma. Tumor cells co-expressed pan-cytokeratin, EMA, and cytokeratin 18, vimentin, protein S100, and smooth muscle actin. The tumor was found to have a very high proliferative activity (Ki-67 was as high as 80%). The disease was fulminant with a fatal outcome 4 months after the occurrence of the first symptoms of the tumor.