Optimizing ALA-PDT in the management of non-melanoma skin cancer by fractionated illumination

De Vijlder, H.C.; Middelburg, T.; De Bruijn, H.S.; Martino Neumann, H.A.; Sterenborg, H.C.J.M.; Robinson, D.J.; De Haas, E.R.M.; De Vijlder, H.C; Middelburg, T; De Bruijn, H.S; Martino Neumann, H.A; Sterenborg, H.C.J.M; Robinson, D.J; De Haas, E.R.M

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Optimizing ALA-PDT in the management of non-melanoma skin cancer by fractionated illumination

De Vijlder, H.C.; Middelburg, T.; De Bruijn, H.S.; Martino Neumann, H.A.; Sterenborg, H.C.J.M.; Robinson, D.J.; De Haas, E.R.M.

Giornale Italiano di Dermatologia e Venereologia Organo Ufficiale Societa Italiana di Dermatologia e Sifilografia 144(4): 433-439

2009

ISSN/ISBN: 0392-0488

PMID: 19755946

Document Number: 635337

The aim of this review was to describe briefly the mechanism and history of photodynamic therapy (PDT). The achieved preclinical and clinical results in Rotterdam are discussed in the light of a search to optimize aminolevulinic acid-photodynamic therapy (ALA-PDT). As the incidence of skin cancer is rising, an optimized treatment in non-melanoma skin cancer is needed.