Morphological and immunohistochemical characteristics of oral mucosa in patients with inflammatory intestinal disorders
Kvetnoĭ, I.M.; Robakidze, N.S.; Kostiuchek, I.N.; Shchukina, O.B.; Proshchaev, K.I.
Klinicheskaia Meditsina 87(11): 49-51
2009
ISSN/ISBN: 0023-2149 PMID: 20143567 Document Number: 635201
The aim of the work was to study morphological and immunological characteristics of oral cavity in patients with Crohn's disease and ulcerative colitis. The group of 40 patients aged 18-64 yr included 30 with Crohn's disease and 10 with ulcerative colitis. They were examined in clinical, endoscopic, morphometric, and immunohistochemical studies. Crohn's disease was shown to be associated with inflammatory processes in the gastrointestinal tract and oral mucosa; in ulcerative colitis, these processes were confined to the colon. It is supposed that inflammation of oral mucosa may be regarded as a separate phenotypic characteristic of Crohn's disease localization with definitive differential diagnostic and prognostic criteria.