Histiocytic sarcoma of the small intestine: Report of one case
Avilés-Salas, A.; Peña-Torres, Mía.de.Lourdes.; Molina-Cruz, A.; Rivas-Vera, S.
Revista Medica de Chile 137(2): 269-274
2009
ISSN/ISBN: 0034-9887 PMID: 19543651 Document Number: 635194
Histiocytic sarcoma (HS) is a rare malignant neoplasm of the lymphohematopoietic system, that occurs in lymph nodes, skin and at extranodal sites, particularly the gastrointestinal tract. Although it shows characteristics histological and immunohistochemical features, it may be misdiagnosed. We report a 67 year-old female patient presenting with colicky abdominal pain and vomiting. A CT scan of the abdomen revealed a tumor in the ileum, that was surgically removed. On pathology, the neoplastic cells displayed large abundant eosinophilic cytoplasm, with bizarre-shaped nuclei, that expressed CD 45, CD 68 and lisozyme. The diagnosis of HS requires the use of a panel of immunohistochemical markers and may be supported by ultrastructural findings.