Management of serum calcium with cinacelet in parathyroid cancer
Vestergaard, P.; Sanden, A.K.
Ugeskrift for Laeger 171(41): 3004-3006
2009
ISSN/ISBN: 1603-6824 PMID: 19814929 Document Number: 635001
Treatment with cinacalcet and intravenous bisphosphonate has improved the previously often fatal prognosis of parathyroid cancer. We report two cases, of which one did not react to treatment and died within a short time-frame. In the other case, cinacalcet controlled serum calcium during a prolonged time period despite metastases. However, increasing doses of cinacalcet combined with more frequent intravenous bisphosphonate were necessary.
Document emailed within 1 workday
Related Documents
Lundgren, E.; Rastad, J.; Ridefelt, P.; Juhlin, C.; Akerström, G.; Ljunghall, S. 1992: Long-term effects of parathyroid operation on serum calcium and parathyroid hormone values in sporadic primary hyperparathyroidism Surgery 112(6): 1123-1129Debruyne, F.; Delaere, P.; Vander Poorten, V. 2001: Postoperative course of serum parathyroid hormone and calcium after surgery for primary hyperparathyroidism Acta Oto-Rhino-Laryngologica Belgica 55(2): 153-157
Kaplan, E.L.; Fang, V.S.; Sugimoto, J.; Fredland, A. 1982: Serum calcium, parathyroid hormone, and urinary cyclic adenosine monophosphate after parathyroidectomy Surgery 92(5): 822-826
D'Amour, P.; Huet, P.M. 1985: Serum calcium does not influence the extraction of 125I-bovine parathyroid hormone by the dog liver in vivo Clinical and Investigative Medicine. Medecine Clinique et Experimentale 8(3): 202-207
Strickland, P.L.; Recabaren, J. 2002: Are preoperative serum calcium, parathyroid hormone, and adenoma weight predictive of postoperative hypocalcemia? American Surgeon 68(12): 1080-1082
Chen, H.J.; Lai, Y.H.; Su, Y.H.; Tsai, J.H. 1985: Study of serum ionized calcium and immunoreactive parathyroid hormone in patients with renal disorders Gaoxiong Yi Xue Ke Xue Za Zhi 1(3): 188-194
Coetzee, J.; Klaff, L.J.; Epstein, S. 1980: Measurement of human serum parathyroid hormone in disorders of calcium metabolism and during administration of certain gut hormones South African Medical Journal 57(5): 165-170
Rodriguez, M.; Lorenzo, V.; Felsenfeld, A.J.; Llach, F. 1986: Changes in serum calcium and phosphorus induced by chronic renal failure in the absence of parathyroid hormone Advances in Experimental Medicine and Biology 208: 383-386
Roth, H.P.; Kirchgessner, M. 1989: Influence of zinc and calcium deficiency on the concentrations of calcitonin, parathyroid hormone, and 25-hydroxy-vitamin D3 in rat serum Journal of Trace Elements and Electrolytes in Health and Disease 3(4): 225-230
Pagliari, B.; Baretta, A.; De Cristofaro, V.; Samà, F.; Cantaluppi, A.; Martis, L.; Imbasciati, E. 1991: Short-term effects of low-calcium dialysis solutions on calcium mass transfer, ionized calcium, and parathyroid hormone in CAPD patients Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis 11(4): 326-329
Brown, E.M.; Gardner, D.G.; Brennan, M.F.; Marx, S.J.; Spiegel, A.M.; Attie, M.F.; Downs, R.W.; Doppman, J.L.; Aurbach, C.D. 1979: Calcium-regulated parathyroid hormone release in primary hyperparathyroidism: studies in vitro with dispersed parathyroid cells American Journal of Medicine 66(6): 923-931
Pols, H.A.; De Jong, M.J.; Juttmann, J.R.; Lockefeer, J.H. 1983: Failure of H2-receptor antagonists to affect serum calcium and immunoreactive parathyroid hormone levels in normal subjects and patients with primary hyperparathyroidism Netherlands Journal of Medicine 26(6): 149-152
Black, H.E.; Capen, C.C.; Arnaud, C.D. 1973: Ultrastructure of parathyroid glands and plasma immunoreactive parathyroid hormone in pregnant cows fed normal and high calcium diets Laboratory Investigation; A Journal of Technical Methods and Pathology 29(2): 173-185
Sriussadaporn, S.; Phoojaroenchanachai, M.; Ploybutr, S.; Plengvidhya, N.; Peerapatdit, T.; Nitiyanant, W.; Vannasaeng, S.; Vichayanrat, A. 2007: Hypercalcemia of malignancy: a study of clinical features and relationships among circulating levels of calcium, parathyroid hormone and parathyroid hormone-related peptide Journal of the Medical Association of Thailand 90(4): 663-671
Horikawa, Y.; Nakajima, H.; Iizuka, K.; Imagawa, A.; Tomita, K.; Shiba, E.; Takai, S.; Miyagawa, J.; Kuwajima, M.; Namba, M.; Hanafusa, T.; Matsuzawa, Y. 1999: In vivo effects of calcium entry blockers on human parathyroid adenoma cells with special reference to calcium sensing ability and the hormone secretion Research Communications in Molecular Pathology and Pharmacology 106(1-2): 87-96
Coen, G.; Mazzuoli, G.F.; Guglielmi, G.; D'Erasmo, E.; Scarda, A.; Paziani, N. 1974: Circadian rhythm of urinary calcium-phosphorus excretion in humans. Role of iodinated hormones, parathyroid hormone, calcitonin, vitamin D and blood calcium levels Folia Endocrinologica 27(6): 507-525
Lindholm, T.S.; Nilsson, O.S.; Lindholm, T.C. 1985: 1-Alpha-OH-cholecalciferol (1-alpha-OH-D3) and optimal calcium intake in calcium deficiency osteoporosis mediated by parathyroid activity morphologic and biochemical changes in adult male rats Acta Vitaminologica et Enzymologica 7(1-2): 39-47
Weber, C.J.; Russell, J.; Costanzo, M.K.; Karp, F.; Benjamin, M.; Hardy, M.A.; Feind, C.R. 1992: Relationships of parathyroid hormone, parathyroid secretory protein, parathyroid hormone messenger RNA, parathyroid secretory protein mRNA, and replication in human parathyroid adenoma and secondary hyperplasia tissues and cultures Surgery 112(6): 1089-1094; Discussion: 1094-1095
Klausner, J.S.; O'Leary, T.P.; Osborne, C.A. 1987: Calcium urolithiasis in two dogs with parathyroid adenomas Journal of the American Veterinary Medical Association 191(11): 1423-1426
Srivastava, V.K.; Srivastava, S.K. 1988: Parathyroid induced regulation of calcium and phosphate in rat lens Indian Journal of Experimental Biology 26(9): 728-729