Genital herpes
Kawana, T.
Nihon Rinsho. Japanese Journal of Clinical Medicine 67(1): 143-152
2009
ISSN/ISBN: 0047-1852 PMID: 19177764 Document Number: 633997
Genital herpes (GH) is the second leading cause of sexual transmitted disease in women and the third in men. About 40% of female genital herpes is caused by herpes simplex virus type 1 (HSV-1) and the remaining by type-2 (HSV-2). Fifty four percent of primary female GH was caused by type-1, whereas 86% of recurrent cases by type-2. For rapid diagnosis of GH, LAMP(loop-mediated isothermal amplification), HSV DNA nuclear amplification method developed in Japan, was applied and favorable results were obtained. We compared three gG based type specific antibody kits (Platteria, HerpeSelect and Captia). Among these, Platteria was shown to be most sensitive and specific.