Infrared spectroscopy of synovial fluid and serum from patients with joint diseases
Cherniakova, I.M.; Pinchuk, L.S.
Klinicheskaia Laboratornaia Diagnostika 9: 17-20; 37
2009
ISSN/ISBN: 0869-2084 PMID: 19882865 Document Number: 633802
The infrared spectra of synovial fluid and serum from the same patient were comparatively analyzed. The coordination bond variations in the complex protein-polysaccharide compounds of synovial fluid were shown to correspond to the range of frequencies of 3000-3500 cm(-1) and those of valence bonds in its individual components were in the range of 800-1700 cm(-1). It was established that a reduction in the peak area of 3300 cm(-1) may be an additional indicator in the diagnosis of osteoarthritis. The above results confirm it expedient to treat joints, by injecting serum-based agents.