Acute abdomen for perforated gastrointestinal stromal tumor (GIST) . A case report
Versaci, A.; Macrì, A.; Grosso, M.; Terranova, M.; Leonello, G.; Ieni, A.; Rivoli, G.; Famulari, C.
Annali Italiani di Chirurgia 80(1): 69-73
2009
ISSN/ISBN: 0003-469X PMID: 19537128 Document Number: 633503
The authors report on a case of voluminous perforated gastrointestinal stromal tumor (GIST) of small intestine and make a review to the light of most recent clinicopathologic advancements. The first clinical manifestation as acute abdomen due to their perforation extremely rare. Gastrointestinal stromal tumor (GIST) represent a rare group of multiform tumors with various biological behaviour. Were identified in the past as leiomyomas, leiomyosarcomas or leiomyoblastomas, has been reclassified on immunochemical features, with a positive expression of Kit (CD117 antigen). Traditionally the prognostic factors of these tumour are: mitotic rate, tumor size and anatomic site. The complete surgical resection and use of imatinib mesylate (Gleevec) are the best available approach.