Lymph node identification in colorectal cancer specimens cases
Schmidt, M.B.; Engel, U.H.øj.; Mogensen, A.M.; Bülow, S.; Petersen, L.N.ør.år.; Holck, S.
Ugeskrift for Laeger 171(35): 2453-2458
2009
ISSN/ISBN: 1603-6824 PMID: 19732529 Document Number: 633430
Colorectal carcinoma is one of the most prevalent malignancies in Western countries. Lymph node status is a significant prognosticator. The chance of identifying node-positivity is positively correlated with the number of lymph nodes (LN) identified. The present paper discusses various variables that may influence the detection of LNs, including patient- as well as surgeon- and pathologist-related issues. The pathologist-related variable most probably shapes the yield the most. Introduction of guidelines focusing on the most appropriate technique may secure better and more consistent results, and the pathologist's commitment is crucial in this respect.