Influence of Solcotrichovac vaccine on formation of neutrophil extracellular traps

Dolgushin, I.I.; Andreeva, I.S.; Ryzhkova, A.I.; Savochkina, A.I.; Mezentseva, E.A.; Nikushkina, K.V.; Abramovskikh, O.S.; Marachev, S.I.; Matveeva, D.N.; Dolgushin, I.I; Andreeva, I.S; Ryzhkova, A.I; Savochkina, A.I; Mezentseva, E.A; Nikushkina, K.V; Abramovskikh, O.S; Marachev, S.I; Matveeva, D.N

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Influence of Solcotrichovac vaccine on formation of neutrophil extracellular traps

Dolgushin, I.I.; Andreeva, I.S.; Ryzhkova, A.I.; Savochkina, A.I.; Mezentseva, E.A.; Nikushkina, K.V.; Abramovskikh, O.S.; Marachev, S.I.; Matveeva, D.N.

Zhurnal Mikrobiologii Epidemiologii i Immunobiologii 4: 53-55

2009

ISSN/ISBN: 0372-9311

PMID: 19715204

Document Number: 632617

To study the influence of Solcotichovac vaccine on formation of neutrophil extracellular traps. Solcotrichovac vaccine administered in various doses was used in order to assess the formation of neutrophil extracellular traps in peripheral blood of women of childbearing age. Therapeutic dose of Solcotrichovac stimulated the most prominent formation of neutrophil extracellular traps. Solcotrichovac vaccine stimulated non-specific arm of mucosal immunity due to formation of neutrophil extracellular traps and it is probable that this mechanism explains the effect of this vaccine.