Efficacy of laparoscopic sleeve gastrectomy on morbidly obese patients with type 2 diabetes mellitus
Li, X.-X.; Rosenthal, R.J.; Zheng, C.-Z.
Zhonghua Wei Chang Wai Ke Za Zhi 12(3): 269-272
2009
ISSN/ISBN: 1671-0274 PMID: 19434536 Document Number: 632498
To evaluate the efficacy of laparoscopic sleeve gastrectomy(LSG) on improving glycemic control of morbidly obese patients with type 2 diabetes mellitus. Prospective study of 30 type 2 diabetes mellitus(T2DM) patients with BMI > or = 35 undergone LSG was carried out. Pre- and post-operative clinical parameters associated with diabetes mellitus 6 months after operation were evaluated. Data collected included demographics, weight loss(BMI, EWL%), diabetes control (FPG, HbA1C) and ghrelin. Fasting plasma glucose and glycosylated hemoglobin concentration tests and clinical outcomes suggested LSG resulted in significant improvement or resolution of T2DM in all the 30 patients with CR 63%(19/30) and PR 37%(11/30). LSG can lead to significant changes in controlling glycemia on morbidly obese patients with T2DM in 6 months. Long-term efficacy needs further follow-up.