Chronic leg ulcers in sickle cell disease: experience in Ibadan, Nigeria
Durosinmi, M.A.; Gevao, S.M.; Esan, G.J.
African Journal of Medicine and Medical Sciences 20(1): 11-14
1991
ISSN/ISBN: 0309-3913 PMID: 1905464 Document Number: 631
The prevalence of chronic leg ulcers was investigated in 872 adults with sickle cell disease (SCD) (630 HbSS and 242 HbSC) at Ibadan, Nigeria. The incidence was 7.5% in HbSS and 1.7% in HbSC patients. The sex ratio in HbSS was 2:1 in favour of males, and three of the four HbSC were females. Ulcers were sited around the ankles in more than 70% of the patients. The duration of the ulcers varied from less than 1 year to more than 20 years. There was no bias for social class. Response to therapy, including autologous skin graft, was poor.
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