Alkaloids from Macleaya cordata
Ye, F.; Feng, F.; Liu, W.
Zhongguo Zhong Yao Za Zhi 34(13): 1683-1686
2009
ISSN/ISBN: 1001-5302 PMID: 19873781 Document Number: 630710
To study the alkaloids of Macleaya cordata. The alkaloids were isolated and purified by various column chromatography as well as recrystallization. Their structures were identified by physico-chemical properties and spectral analysis. Thirteen alkaloids were isolated and identified as 6-methoxy-dihydrosanguinarine (1), norsanguinarine (2), 6-acetonyl-dihyrochelerythrine (3), 6-acetonyl-dihyrosanguinnarine (4), sanguidimerine (5), chelidimerine (6), (+/-) -bocconarborine A (7), (+/-)-bocconarborine B (8), cryptopine (9), dihydrosanguinarine (10), dihydrochelerythrine (11), protopine (12), alpha-allocryptopine (13). Compounds 2, 3, 5 - 9 were firstly isolated from the genus Macleaya and compound 1 was obtained from M. cordata for the first time.