Study on Diels-Alder type adducts from stem barks of Morus yunanensis
Cui, X.; Chen, H.; Chen, R.
Zhongguo Zhong Yao Za Zhi 34(3): 286-290
2009
ISSN/ISBN: 1001-5302 PMID: 19445150 Document Number: 630413
To isolate and identify the Diels-Alder type adducts from stem barks of Morus yunanensis. The compounds were isolated and purified by silicagel, Sephadex LH-20 and RP-18 colum chromatography. Their chemical structures were elucidated on the basis ofphysicochemical properties and spectral data. Nine compounds were isolated and identified as: kuwanon G (1), sanggenol M (2), mulberrofuran J (3), guangsangon B (4), resveratrol (5), kuwanon X (6), kuwanon P (7), mulberrofuran O (8), mulberrofuran Q (9). All the compounds are isolated from the plant for the first time, and compounds 4, 5 have anti-inflammation activities with inhibitory ratios of 57.3%, 50.5% respectively at a concentration of 10 microg mL(-1).